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Recent emerging evidence suggests that a group of predominantly liver-derived proteins called hepatokines directly affect the progression of atherosclerosis by modulating endothelial dysfunction and infiltration of inflammatory cells into vessel walls

Incorporating omega 3 supplements during GLP-1 treatment can also support cognitive functions and help mitigate the natural inflammation that accompanies metabolic adjustments

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The STEP 4 trial published in JAMA showed that participants maintained significant weight loss over 68 weeks when continuing the medication
