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A deficit driven by eating nutrient-dense foods (lean proteins, veggies, whole grains, etc.) will feel better and preserve muscle mass more than a deficit from, say, skipping meals but eating junk food when you do eat

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Little, T

7,917,43,58 Conversely, the slight but significant increase in heart rate and possibly other effects have been associated with a neutral, if not untoward in some cases, effects of GLP-1 RAs in patients with HFrEF