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NIT-1 cells were incubated with the JC-1 staining solution for 20 min at 37 C and then rinsed with JC-1 staining buffer

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Consequent endothelium damage results in increased permeability of the endothelium due to disruption of cellcell junction (18)

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Understanding Semaglutide and Berberine Mechanisms Semaglutide (the active compound in Ozempic) works by mimicking glucagon-like peptide-1, a hormone that slows stomach emptying, reduces appetite, and improves blood glucose control

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Insulin dosage did not change for the placebo group

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