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Although these agents produce substantial and sustained weight reduction, emerging clinical observations suggest that chronic therapy may be accompanied by changes in lean mass trajectory, reduced protein intake, and micronutrient insufficiency

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Biomedicines 10(2):289 Stoi-Grujii S, Maksimovi D, Badovinac V, Samardi T, Trajkovi V, Luki M et al (2001) Antidiabetogenic effect of pentoxifylline is associated with systemic and target tissue modulation of cytokines and nitric oxide production
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