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REWIND, Researching Cardiovascular Events With a Weekly Incretin in Diabetes

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The STEP 1 trial reported an average body-weight reduction of 14.9% with branded injectable semaglutide 2.4 mg over 68 weeks

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The cardiovascular side effects that sank sibutramine are still being studied

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The good news is that GLP-1 accessibility is improving

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FIGURE 1 3.3 Signal values associated with different GLP-1 RAs We identified signals of AP events associated with all GLP-1 RAs using the criteria established by the four algorithms, and the results are summarized in Table 3

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