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PBH pathophysiology implicates heightened insulin and glucagon-like peptide 1 (GLP-1) levels, with bile acids (BA) contributing to GLP-1 release

Solid phase sandwich ELISA for the determination of GLP-1 (9-36/37) in human, mouse, and rat EDTA plasma and cell culture supernatant

Semaglutide offers a novel therapeutic avenue for obese HFpEF patients, improving symptoms, function, and quality of life compared with existing therapies such as SGLT2 inhibitors, MRAs, and ARNIs
