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Description
SURPASS-4 also addressed CV safety via the composite endpoint of major adverse cardiovascular events (MACE), discussed further below
Never double doses to compensate for a missed injection
The disadvantage is larger injection volumes, which some researchers find uncomfortable
Each medication affects glycemic control through slightly different mechanisms
The results revealed a significant and dose-dependent reduction of amyloid plaques in the lecanemab group (10 mg/kg, intravenous infusion every 2 weeks) from baseline to week 79 compared with the placebo group
