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Since the IRA gives biologics a 12-year safe harbor from negotiations, which aligns with the biologic exclusivity provided by the Biologic Price Competition and Innovation Act, it creates a scenario in which the innovator could be facing negotiations just as its first biosimilar competition prepares to launch

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At each stage, the residues are blocked off with protecting groups to avoid cross-reactions

[DOI] [PMC free article] [PubMed] [Google Scholar] 80.Yu EW, Lee MP, Landon JE, Lindeman KG, Kim SC

Retrieved from Januszewski, J., Forma, A., Zembala, J., et al