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A network meta-analysis suggests retatrutides greater efficacy compared to other GLP-1RAs, though head-to-head trials are needed for definitive conclusions

Keywords: GLP-1RAs, GLP-1/GIP dual receptor agonist, tirzepatide, clinical pharmacology, T2DM, obesity, neuroprotection Introduction Glucagon-like peptide-1 (GLP-1) is a small-peptide hormone