how long has glp 1 been around for GLP-1 to Kick In: Timeline and What to Expect The History of GLP-1s
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DOI: 10.3390/nu15224809

These effects are greater than those seen with older weight loss medications (typically ~5% total weight loss) and close to typical weight loss seen with bariatric surgery
It is acknowledged that activation of STAT3 which is crucial to M2 phenotype transformation, while STAT1 activity which is a key determinant for the M1 subtype
