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It highlights key findings that can inform our understanding of these substances and inform harm reduction strategies

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THE BOTTOM LINE GLP-1 medications work best with a nutrition strategy behind them These medications are a tool, not a complete solution

Patients should be informed about the expected side effect profile before initiating therapy

A critic to the use of a murine model deficient for intestinal GCG products, would be that other gut hormones might compensate for the lack of a functional GCG gene in that tissue, hence explaining the normalized incretin effect