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Before GLP-1 Therapy Even with a consistently healthy diet, JH struggled with the daily limitations caused by lipedema

Aetna Medicare plans (including Medicare Advantage Part C and Medicare Part D prescription drug plans (PDPs) generally cover Ozempic when prescribed for type 2 diabetes, aligning with both Medicare and FDA-approved indications

The different ones GI discontinuation rate: 5.6% of semaglutide (Wegovy) users stopped due to GI side effects, vs 2.7% of Tirzepatide (Mounjaro) users Diarrhoea: Common with Mounjaro because of its dual action Nausea and constipation: Seen more in Wegovy MHRA NAION warning (February 2026) : Both medications carry an updated warning about a very rare but serious eye condition (non-arteritic anterior ischaemic optic neuropathy)

They work through several important mechanisms: They increase insulin release from the pancreas when blood glucose is high They reduce excess glucose release from the liver They slow stomach emptying, helping prevent sharp glucose spikes after meals They increase feelings of fullness, often reducing appetite Because these effects depend on blood glucose levels, GLP-1 medications on their own carry a very low risk of causing low blood sugar (hypoglycaemia)

Liver cirrhosis can be defined as the end stage of chronic liver diseases and is caused by progressive fibrosis