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Future GLP-2 trials in IBD should stratify patients by disease phenotype (mucosal UC, inflammatory CD, stricturing CD) and incorporate serial cross-sectional imaging to monitor for stricture progression, given the mechanistic link between GLP-2R signaling through subepithelial myofibroblasts and intestinal fibrogenesis

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Saliva washout reduces bioavailability unless specialized formulations are used

Seek immediate medical attention if you experience any symptoms of a serious allergic reaction, including : Swelling of the eyes, face, mouth, tongue, or throat Hives or itchy skin Wheezing or difficulty breathing Lightheadedness Changes in pulse (rapid or weak pulse) Hypoglycemia Ozempic carries a very low risk of hypoglycemia , particularly in people who do not have diabetes