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Am J Clin Oncol

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Triple Agonist Treatment Due to the success of both DualAG approaches and the generally high sequence homology between GLP-1, GIP, and glucagon, the next step in novel pharmaceutical development was the design of chimeric GLP-1R/GIPR/GcgR unimolecular triple-agonists followed by the development of another triple agonist, a GLP-1/glucagon/Y2 receptor triple agonist [85]

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