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But: Semaglutide if: You prefer a tried-and-tested therapy You have type 2 diabetes and desire dual gain You are cautious about newer drug side-effects Select Tirzepatide if: You desire maximal weight loss effect You experience ongoing hunger and cravings You are receptive to newer, dual-mechanism therapy Always see a licensed healthcare professional or obesity medicine specialist to decide on the proper therapy for your individual needs and medical history

- Structural Modifications: C-terminal amidation (C225H348N48O68)

But those taking a GLP-1 for weight loss may think about reducing their dose or even stopping completely once they reach their goal weight

Effects of subcutaneous tirzepatide versus placebo or semaglutide on pancreatic islet function and insulin sensitivity

Rapid weight loss may result in telogen effluvium and temporary hair shedding