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Consider a brief diet break or a temporary increase in calories to reset metabolism

Cochair of International Federation for the Surgery for Obesity and Metabolic Diseases European Chapter

Most patients begin at 0.25 mg weekly, with the dose increasing every four weeks until reaching the maintenance dose of 2.4 mg

The review delves into the intricacies of different modification approaches, including N and C-terminal modifications, Fatty acid Side chain Modifications, and Large Molecule Conjugation Modifications, highlighting their rationale and resulting improvements in half-life, stability, receptor binding, and bioactivity
