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Some researchers also explore tirzepatide with B12 to support energy levels and prevent deficiency during rapid weight loss

Key monitoring parameters should include frequency and severity of binge episodes (using standardized measures such as the Binge Eating Scale or Eating Disorder Examination-Questionnaire), weight and metabolic parameters, gastrointestinal side effects, mood and anxiety symptoms, and importantly, any emergence of new disordered eating patterns such as restrictive eating or compensatory behaviors

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The medical community even has a term for it: sarcopenic obesity, where someone carries excess fat but insufficient muscle
