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This glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist is a large peptide molecule that is not targeted by conventional immunoassay-based urine drug screens used in employment, athletic, or routine clinical settings

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144 It is correct to state that somatostatin does reduce the incretin effect as it suppresses GIP and GLP-1 release from the GIT, giving it an indirect role in dampening insulin secretion

Patients should be cautious of marketing claims suggesting natural supplements can replace prescribed treatments