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Key pathways include cAMP/PKA/CREB, PI3K/AKT, and MAPK/ERK
The increase in oxidative stress is implicated in many pathological conditions associated with RAAS hyperactivation, such as endothelial dysfunction (79), cardiac hypertrophy (80), and diabetic nephropathy (81)
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Its a big deal for the people it covers
Exendin-4, though, stuck around
