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Among patients with PCOS who were prescribed a GLP-1, 83.5% experienced an HbA1c reduction, compared to only 55.9% of those prescribed metformin

In clinical trials where a GLP-1 RA was added to background basal insulin, a general 20% basal insulin reduction in all patients or a 20% reduction in patients with an A1C 8.0%, the GLP-1 RA can be reasonably initiated without a reduction in the basal insulin dose for many patients

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Each n represents a biological replicate from 6 ( A and B ), 5 ( C and D ), 1 ( E and F ), and 4 ( G and H ) independent cohorts of sex- and age-matched animals