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Topline results announced in December 2025 were positive, showing that patients who switched from injectables to oral orforglipron maintained their weight loss

The GLP-1 RA group consisted of patients receiving GLP-1 RAs, including exenatide, dulaglutide, and liraglutide

Stress management : Techniques like meditation, yoga, and deep breathing can reduce stress, which can be a barrier to weight loss

References Semaglutide: uses, dosage, side effects, brands

And depending on symptoms, your clinician may recommend checking thyroid levels, testing for sleep apnea, or reviewing your medications to evaluate for other causes of weight change