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Within-design inconsistency was not statistically significant (Q=5.52
Wet AMD , though less common, is more aggressive and involves abnormal blood vessel growth beneath the retina (choroidal neovascularization), which can leak fluid or blood, causing rapid and severe vision loss if untreated
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SURMOUNT-1 Tirzepatide The pivotal tirzepatide trial, published in the New England Journal of Medicine in 2022, randomized 2,539 adults with obesity to tirzepatide 5 mg, 10 mg, 15 mg or placebo for 72 weeks
[PubMed] 4.Gillman PK
