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Difficulty in maintaining results after ceasing treatment

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For researchers starting a comparative protocol, the practical implication is that tirzepatide offers a broader reference base for benchmarking assay performance and expected magnitudes of effect, while retatrutide provides a more mechanistically novel reference for triple-agonist work

While the "Ozempic baby" headlines might make it sound like these drugs have a direct, magical effect on the ovaries, the reality is rooted in metabolic science

doi: 10.3803/EnM.2016.31.2.258