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they are related to focal areas of glial reaction, inflammation, and demyelination (Reich et al., 2018)
Real-world evidence: Verana Health, TriNetX, and nference
Transparency matters: not to overpromise results, but to make visible what has actually been done
Tirzepatide use increased over time, consistent with broader population trends (15)
Clinical trial data show that gastrointestinal adverse effectsincluding nausea, vomiting, diarrhea, and abdominal discomfortoccur in 20-50% of patients initiating GLP-1 therapy, with rates varying by specific agent and dose
