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Conservative measures like exercise, diet and behavioral modifications are some of the initial ways to lose weight

In contrast, patients using metformin or insulin probably have less or more advanced diabetes, which would increase the risk of unmeasured confounding by diabetes severity and baseline risk of hyperkalemia

2022 Aug 3;7(11):2345-2355

Economic Implications and Access Challenges Cost Considerations The economic burden of GLP-1 agonists represents a significant barrier to widespread adoption

10.1007/s10787-022-00956-6 Inflammopharmacology 4 Aviles-OlmosI.DicksonJ.KefalopoulouZ.DjamshidianA.EllP.SoderlundT.et al (2013)
