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Appetite effects versus weight effects An important distinction from the research: appetite reduction precedes weight loss

The insulin-per-kilogram proxy is a clean, useful gauge, but it is a proxy for a clamp it cannot reproduce, and it is blind to residual C-peptide unless you account for it
Perez-Cruz C, Nolte MW, van Gaalen MM, Rustay NR, Termont A, Tanghe A, et al

Never inject into areas that are bruised, tender, swollen, or scarred from previous injections, as these tissues cannot absorb medication effectively

Why Non-Overweight Patients Qualify for GLP-1 Therapy GLP-1 medications were originally developed for type 2 diabetes management and have proven cardiovascular benefits independent of weight loss
