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Much anticipated Phase II results in obesity for Amgens GLP-1 agonist/GIP antagonist showed up to 20% weight loss, but without detailed data the drugs competitiveness is hard to ascertain.

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The use of glucagon-like peptide-1 receptor agonists (GLP-1RAs), used to treat diabetes and obesity, may be associated with a wide range of health effects, both positive - such as a reduced risk of cardiometabolic disorders - and negative - an increased risk of gastrointestinal conditions or hypertension