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Dupilumab may be an alternative option in the treatment of acquired reactive perforating collagenosis combined with AD

The schematic diagram summarizes the main mechanistic areas, including adipocyte lipid handling and fatty acid flux, mitochondrial biogenesis and oxidative capacity, beige adipocyte programming, immunometabolic remodeling, adipokine/cytokine regulation, and extracellular matrix (ECM) dynamics, and illustrates their functional relationships

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Crohns disease is basically a disease of the immune system