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GLP-1 directly raises sympathetic tone, increasing heart rate independently of metabolic demand

Why Muscle Matters During GLP1Related Weight Loss The report shows that while GLP1 medications are effective for reducing body weight, a meaningful portion of that loss can come from lean mass

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Purpose of Review This review will summarize the most contemporary trials for glucagon-like peptide 1 receptor agonists (GLP1-RA) and sodium-glucose cotransporter 2 inhibitors (SGLT2-i) and present guidance on management and recommendations on adjunctive tapering of insulin in patients with insulin-dependent diabetes mellitus, which we term de-insulinization. Recent Findings GLP1-RA and SGLT2-i are the principal classes of diabetes medications evidencing cardiovascular benefit