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doi: 10.1038/nrm3512 8 AndersonRG

This approach isn't suitable for everyone, particularly those with diabetes on insulin or sulfonylureas, pregnant or breastfeeding women, people with a history of eating disorders, those with kidney disease, or frail individuals

Lancet 2016

And the interesting thing is that the difference between those two is the exact same difference between the uncasted leg and the casted leg for the ones who had had normal food, but just they had gone through the caloric restriction

Omer Cavus, The Ohio State University, United States Updates Copyright 2022 Schnenberger, Cossu, Prendin, Cappon, Wu, Fuchs, Mayer, Herzig, Facchinetti and Bally