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In humans, GLP-1Rs are found in a variety of tissues, including pancreatic islets, the lungs, the kidneys, the gastrointestinal tract, the central nervous system, the vagus nerve, endothelial cells and smooth muscle cells, as well as in atrial and ventricular cardiomyocytes

Today, GLP-1s are widely prescribed as safe and effective weight-loss therapies that work by enhancing the bodys natural ability to regulate appetite, metabolism, and blood sugar

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