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Skipping dose escalation : Advancing too quickly through the titration schedule or starting at maintenance doses dramatically increases gastrointestinal adverse effects and treatment discontinuation

GLP-1 agonists should be discontinued if pancreatitis is suspected

As they get older (or after a woman gives birth), the pain usually improves

Retatrutide-specific discontinuation data is limited, but there is no reason to expect a fundamentally different trajectory given the shared receptor biology
