glp-1 and dual glp-1/gip receptor agonists The Emerging Role of GIP in Glycemic Management and Cardiovascular Risk Reduction GLP-1 & GIP Agonists |

10.1053/j.ajkd.2024.11.013 14 ChengC

353 These findings confirm that in the synovium, GLP-1R is expressed on two different cell types, macrophages and fibroblast-like synoviocytes, which are specialized cells distributed within the synovial intima and subintima, and these cell types play important roles in hyaluronic acid synthesis, metabolite processing, and clearance of matrix degradation fragments

These findings suggest that GLP-1 RAs may be more effective in reducing MI risk, primarily among patients with known ASCVD

95% CI, 0.67-2.17)

GLP-1s (glucagon-like peptide-1 receptor agonists) are medications that mimic natural gut hormones involved in appetite regulation, insulin signaling, and digestion