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It is also indicated to reduce the risk of stroke, heart attack, and death in patients with diabetes and cardiovascular disease, says Katherine H

Overall, these results are in line with enhanced GLP-2R action, previously shown to increase villus length by promoting intestinal cell proliferation and inhibiting apoptosis at the villus tip 17

Are gastrointestinal symptoms related to diabetes mellitus and glycemic control

Depending on the reason, the next move might be: Resubmitting with better documentation Trying a different covered medication Completing the required lifestyle program over the next 3 to 6 months Filing a formal appeal with new clinical evidence Switching to cash-pay or manufacturer programs Pausing the GLP-1 path and addressing an underlying mental health, hormonal, or metabolic issue first Considering a different FDA-approved weight loss medication The right next step depends on your specific plan, BMI, health history, prior medication trials, and treatment goals