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Pegylated forms of Exedin-4 can significantly reduce organ damage caused by sepsis (cecal ligation and puncture model) by decreasing vascular permeability and inhibiting the interaction between leukocytes and endothelial cells (40)
Goutzourelas N et al
A study from 2019 shows a differential genome wide gene expression pattern of human fungiform taste buds between lean and obese which includes Shh [3]
doi: 10.1056/nejm199909163411204
