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GLP-1 affects satiety, gastric emptying, and insulin secretion GIP appears to act more directly on fat tissue and insulin sensitivity By activating both, tirzepatide may: Enhance appetite suppression Improve insulin sensitivity beyond weight loss alone Alter fat metabolism differently than GLP-1 alone This doesnt mean better for everyone, but it helps explain trial outcomes

The combined SUSTAIN, FLOW, and PIONEER trial programs have enrolled more than 15,000 patients and consistently demonstrated benefits beyond glycemic control, including reduced cardiovascular events, slower progression of kidney disease, and modest weight loss

It was a very quick & fluid process

Can I use semaglutide to lose a small amount of weight