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This is why the STEP trial protocol includes two intermediate doses (1.7 mg) before reaching 2.4 mg, and why many people find their sweet spot below maximum

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We'll explore its specific uses and how it differs from dual-agonist therapies

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Weight changes: Do not expect dramatic weight loss in the first month at 2.5mg

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Tirzepatide operates through dual GLP-1 and GIP receptor agonism , a mechanism that already outperforms standalone GLP-1 drugs like semaglutide in head-to-head trials

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Cravings diminish

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