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Oral semaglutide, taken daily, may take slightly longer to show effects compared to the injectable version

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MWN-109 is a synthetic peptide in Phase 2 since August 2025, with a concurrent Phase 1b MAD study

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Persistence remains mixed: a 2024 real-world study found 32% on therapy at 1 year among non-diabetic users, and according to Prime Therapeutics, only 1 in 12 remain at 3 years