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Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo

Common signs of gallbladder dysfunction can include: Pain in the right upper abdomen, especially after eating Nausea or vomiting following fatty meals Bloating or discomfort that comes and goes Patients with a history of gallbladder disease, those who experience rapid weight loss, or those taking other medications that affect bile metabolism may be at higher risk

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As these medications slow gastric emptying, relative contraindications include history of recurrent pancreatitis and gastroparesis

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