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At 26 weeks, the mean weight loss was 8.6% in the 12 mg orforglipron group, 11.2% in the 24 mg orforglipron group, 12.3% in the 36 mg orforglipron group and 12.6% in the 45 mg orforglipron group compared with 2% for those receiving placebo
J Diabetes (2015) 7(3):32939
References [1] Teigen LM, Biruete A, Khoruts A
Weight loss compared to placebo was ~5% in RCTs
Metallo Christian M, Vander Heiden Matthew G
