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To view a copy of this licence, visit About this article Cite this article Pugliese, G., de Alteriis, G., Muscogiuri, G

Appetite hormones like ghrelin begin rising back toward baseline

Human endogenous GLP-1 cleaves GLP-1 (7-36 amide) and GLP-1 (7-37) on the N-terminal dipeptide very quickly in the presence of dipeptidyl peptidase 4 (DPP-4), generating low-affinity ligands of the GLP-1 receptor, GLP-1 (9-36 amide) or GLP-1 (9-37), which gives it a half-life of only 1.5 min2 min (Kieffer et al., 1995

Pale yellow to nearly clear urine indicates adequate hydration

Low muscle mass increases the risk of falls, fractures, and functional decline as we age, and it may also make it harder to maintain the weight loss long term