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Benzodiazepines, antidepressants, and marijuana, for example, can suppress this stage of sleep and therefore lead to REM rebound later on

There is experimental evidence that pharmacological treatments targeting insulin resistance, such as metformin and sulfonylureas [15, 16], may improve asthma management [8]

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As for the effects of chronic fat intake on GIP secretion, the expression of regulatory factor X 6 (Rfx6) and pancreatic and duodenal homeobox 1 (Pdx1), important transcription factors involved in GIP expression [67-69], was found to be increased in GIP-producing cells in high-fat diet (HFD)-induced obese mice, suggesting a possible mechanism for GIP hypersecretion in obesity [68, 70]