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doi: 10.1021/acs.jmedchem.7b00174
15 Modeling data suggest that loss of muscle mass varies by sex, representing 10-15% of total weight reduction in females and 20-25% of total weight reduction in males, in the absence of structured strength training
Available from: Wilding JPH, Batterham RL, Calanna S
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52 These results, in part, supported the development of orforglipron as an orally delivered GLP-1RA in clinical testing