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In addition to weight loss, tirzepatide has shown significant efficacy in improving glycemic control, with many patients achieving target HbA1c levels below 7%

3 GLP-1R localization and mechanistic pathways in metabolic and behavioral regulation GLP-1 Rs exhibit high expression in pancreatic -cells in both rodents and humans, where they play a pivotal role in mediating glucose-dependent insulin secretion (Nauck et al., 1993

Patients are encouraged to report any suspected side effects from GLP-1 medications via the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk or via the Yellow Card app)

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While not yet FDA-approved for liver conditions, these agents improve metabolic parameters that influence hepatic health