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Nevertheless, GLP-1 presented a rather ephemeral circulatory half-life, lasting a mere 12 min, due to the rapid enzymatic degradation by dipeptidyl peptidase IV (DPP-4), which markedly limits its biological efficacy [3,4,5]

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While not officially listed as a side effect for all these drugs, many patientsparticularly those using tirzepatidereport significant decreases in saliva production

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