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Primary prevention of cardiovascular and heart failure events with SGLT2 inhibitors, GLP-1 receptor agonists, and their combination in type 2 diabetes

Big pharma has also hit this stumbling blockSanofis shot on goal for a GLP-1 RA was halted in Phase 2 studies due to even higher GI toxicity
Olsen MB, Hovelmann U, Griffin J, Knudsen KM, Johansen T, Kendall D, et al
GLP-1 fatigue management strategies can help

Declines were observed for both pulmonary embolisms and DVTs
