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Mechanisms of Lean Mass Reduction During Pharmacologically Induced Weight Loss Reductions in lean mass during GLP-1 receptor agonist-associated weight loss are best understood within the broader physiological framework of sustained negative energy balance

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For users with prediabetes or metabolic syndrome (common reasons for starting semaglutide), this blood sugar instability can trigger fatigue, shakiness, or even loss of consciousness

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This article is part of the Medical Insights vertical on Op-Med, which features study breakdowns, resources, and insights from Doximity members on popular topics in medicine

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By lowering both, GLP-1s may help preserve fertility in ways unrelated to weight loss or insulin sensitivity

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