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In diet-induced obese mice treated with a long-acting GIPR agonist, circulating triglyceride levels were reduced during oral lipid challenge, and lipoprotein-derived fatty acid uptake into adipose tissue was increased

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These medications work by slowing gastric emptying, which helps regulate blood sugar levels and promotes a feeling of fullness
doi: 10.1161/HYPERTENSIONAHA.120.12858 136 DaviesMFrchLJeppesenOKPaksereshtAPedersenSDPerreaultLet al
All participants, investigators and the sponsor were masked to treatment assignment