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Moreover, GIP has been found to boost glucose uptake by improving insulin sensitivity in adipocytes (176, 177), while tirzepatide has been demonstrated to enhance insulin sensitivity and promote glucose disposal in white adipose tissue in Glp-1r-null mice (178), further supporting a direct effect of GIP on adipose tissues

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Conversely, if you feel consistently nauseated, fatigued, or unable to eat enough to maintain nutrition, dose reduction is appropriate
