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Earlier versions of GLP-1 drugs, such as exenatide (Byetta), increased the risk for pancreatic cancer or certain types of thyroid cancer and even instances of autoimmunity

The same IU on two different vials can mean very different milligram doses

Patients with obesity have yet another option in their arsenal to fight access weight that is not only very effective but also seems relatively safe, at least in the short and medium term

Meanwhile, newer mechanisms, including muscle-preserving combinations and multi-agonist approaches, are being explored to differentiate future entrants and address limitations such as lean mass loss